A graduate of the Yale School of Drama and the University of Illinois, Tom Isbell spent his professional career acting in theatre, film and TV, working opposite Robert DeNiro, Ed Harris, Helen Hunt, Lynn Redgrave, Rosemary Harris, Hal Holbrook, Anne Bancroft, Sarah Jessica Parker, John Turturro, Angela Bassett and others. TV credits include Designing Women, L.A. Law, Golden Girls, Murder She Wrote, Coach, Family Ties, Columbo and recurring roles on Jake and the Fat Man and Sisters. Film credits include 84 Charming Cross Road, Jacknife, Clear and Present Danger, The Abyss and True Lies. He was also the subject of a PBS documentary, Starting in Innocence.

He has written and performed three one-person plays, including Me & JFK, which has been produced in New York, Los Angeles and Egypt. With John Ahart, he co-authored Walt Whitman and the Civil War, which premiered at the Great American People Show in 1995.

As a director, Isbell has taken two productions to the Kennedy Center as part of the Kennedy Center American College Theater Festival (KCACTF): Dear Finder, a documentary play about the Holocaust, and The Movie Game, written by Adam Hummel. He is the former National Playwriting Program chair for Region V of KCACTF.

An associate professor at the University of Minnesota Duluth, he was recently named the Albert Tezla Scholar/Teacher of the Year, as well as a Horace T. Morse Distinguished Teacher, the highest undergraduate teaching honor given within the University of Minnesota. He is happily married to Pat Isbell, who is both an actress and elementary school teacher.